Dichloromethane → Tert-butyl 3-hydroxy-4-(methylsulfonyloxymethyl)pyrrolidine-1-carboxylate

HRID 1132369Notes

Reaction equation

HRID 1132369 reaction equation
[C:13]([CH3:14])([CH3:15])([CH3:16])[O:17][C:18](=[O:19])[N:20]1[CH2:21][CH:22]([OH:27])[CH:23]([CH2:25][OH:26])[CH2:24]1.[CH3:1][S:2]([Cl:3])(=[O:4])=[O:5].[CH3:6][CH2:7][N:8]([CH2:9][CH3:10])[CH2:11][CH3:12].[Cl:28][CH2:29][Cl:30]>>[CH3:1][S:2](=[O:4])(=[O:5])[O:26][CH2:25][CH:23]1[CH:22]([OH:27])[CH2:21][N:20]([C:18]([O:17][C:13]([CH3:14])([CH3:15])[CH3:16])=[O:19])[CH2:24]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 23125669HCID 23125669, compound

Product 1

HCID 76723093Tert-butyl 3-hydroxy-4-(methylsulfonyloxymethyl)pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-ebfac197e54d4be2b7361b0bda52158f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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