Toluene → 6-Bromo-4-chloro-3-methanesulfonyl-2-methyl-quinoline

HRID 1133123Notes

Reaction equation

HRID 1133123 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([OH:17])[c:6]([S:13](=[O:14])(=[O:15])[CH3:16])[c:7]([CH3:12])[n:8][c:9]2[cH:10][cH:11]1.[CH3:18][N:19]([CH3:20])[c:21]1[cH:22][cH:23][c:24]([CH3:25])[cH:26][cH:27]1.[CH3:33][c:34]1[cH:35][cH:36][cH:37][cH:38][cH:39]1.[P:28]([Cl:29])([Cl:30])([Cl:31])=[O:32]>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([Cl:30])[c:6]([S:13](=[O:14])(=[O:15])[CH3:16])[c:7]([CH3:12])[n:8][c:9]2[cH:10][cH:11]1

Participants

5

Reactant 4

HCID 1140TolueneHCID 7471Dimethyl-p-toluidineHCID 24813Phosphorus oxychlorideHCID 178432088HCID 178432088, compound

Product 1

HCID 120016236-Bromo-4-chloro-3-methanesulfonyl-2-methyl-quinoline

Sources & evidence

ORD record
ord-2f79dd99c6f446dd8b73063410575c7f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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