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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1133187Generated: October 26, 2026

Dimethylformamide → 2-Amino-4-{4-[(1-[2-fluoro-5-trifluoromethyl-phenyl]-methanoyl)-amino]-phenyl}-thiophene-3-carboxylic acid amide

https://huagongshe.com/reaction/1133187

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
ReactantHexafluorophosphateHCID 9886—
ReactantO-benzotriazol-1-yl-tetramethyluroniumHCID 130500—
Reactant2-Fluoro-5-(trifluoromethyl)benzoic acidHCID 688292—
Reactant2-Amino4-(4-amino-phenyl)-thiophene-3-carboxylic acid amideHCID 69258890—
Product2-Amino-4-{4-[(1-[2-fluoro-5-trifluoromethyl-phenyl]-methanoyl)-amino]-phenyl}-thiophene-3-carboxylic acid amideHCID 10137100—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-1702f785fb164e78b50b35fe8a7dd7da
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)