Dimethylformamide → 2-Amino-4-{4-[(1-[2-fluoro-5-trifluoromethyl-phenyl]-methanoyl)-amino]-phenyl}-thiophene-3-carboxylic acid amide
Reaction equation
[CH3:55][CH2:56][N:57]([CH2:58][CH3:59])[CH2:60][CH3:61].[F:17][c:18]1[c:19]([C:20](=[O:21])[OH:22])[cH:23][c:24]([C:27]([F:28])([F:29])[F:30])[cH:25][cH:26]1.[NH2:1][c:2]1[s:3][cH:4][c:5](-[c:10]2[cH:11][cH:12][c:13]([NH2:16])[cH:14][cH:15]2)[c:6]1[C:7](=[O:8])[NH2:9].[O:62]=[CH:63][N:64]([CH3:65])[CH3:66].[P-:31]([F:32])([F:33])([F:34])([F:35])([F:36])[F:37].[n:38]1([O:39][C:40]([N:41]([CH3:42])[CH3:43])=[N+:44]([CH3:45])[CH3:46])[c:47]2[cH:48][cH:49][cH:50][cH:51][c:52]2[n:53][n:54]1>>[NH2:1][c:2]1[s:3][cH:4][c:5](-[c:10]2[cH:11][cH:12][c:13]([NH:16][C:20]([c:19]3[c:18]([F:17])[cH:26][cH:25][c:24]([C:27]([F:28])([F:29])[F:30])[cH:23]3)=[O:21])[cH:14][cH:15]2)[c:6]1[C:7](=[O:8])[NH2:9]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-1702f785fb164e78b50b35fe8a7dd7da
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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