Bicarbonate Ion → tert-butyl 2-formyl-4H,5H,6H,7H-thieno[3,2-c]pyridine-5-carboxylate

HRID 1133188Notes

Reaction equation

HRID 1133188 reaction equation
[C:19](=[O:20])([O-:21])[OH:22].[CH3:24][C:25]1([CH3:34])[N:26]([O:27])[C:28]([CH3:29])([CH3:30])[CH2:31][CH2:32][CH2:33]1.[Cl:35][O-:36].[Cl:38][CH2:39][Cl:40].[Na+:23].[Na+:37].[OH2:41].[OH:1][CH2:2][c:3]1[cH:4][c:5]2[c:10]([s:11]1)[CH2:9][CH2:8][N:7]([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:6]2>>[O:1]=[CH:2][c:3]1[cH:4][c:5]2[c:10]([s:11]1)[CH2:9][CH2:8][N:7]([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:6]2

Participants

8

Reactant 7

HCID 769Bicarbonate IonHCID 923Sodium ion2×HCID 962WaterHCID 6344DichloromethaneHCID 61739HypochloriteHCID 5499762,2,6,6-Tetramethylpiperidin-1-olHCID 118456061,1-Dimethylethyl 6,7-dihydro-2-(hydroxymethyl)thieno[3,2-c]pyridine-5(4H)-carboxylate

Product 1

HCID 11845085tert-butyl 2-formyl-4H,5H,6H,7H-thieno[3,2-c]pyridine-5-carboxylate

Sources & evidence

ORD record
ord-1f5faa41899844d6b3b385b55d8dda81
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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