Piperidine → 1-(4-Methoxy-2-trifluoromethyl-phenyl)-piperidine
Reaction equation
[Br:1][c:2]1[c:3]([C:10]([F:11])([F:12])[F:13])[cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1.[CH2:14]1[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]1.[CH2:20]1[O:21][CH2:22][CH2:23][O:24][CH2:25]1.[O:28]=[C:29]([CH:30]=[CH:31][c:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1)[CH:38]=[CH:39][c:40]1[cH:41][cH:42][cH:43][cH:44][cH:45]1.[O:46]=[C:47]([CH:48]=[CH:49][c:50]1[cH:51][cH:52][cH:53][cH:54][cH:55]1)[CH:56]=[CH:57][c:58]1[cH:59][cH:60][cH:61][cH:62][cH:63]1.[O:64]=[C:65]([CH:66]=[CH:67][c:68]1[cH:69][cH:70][cH:71][cH:72][cH:73]1)[CH:74]=[CH:75][c:76]1[cH:77][cH:78][cH:79][cH:80][cH:81]1.[Pd:26].[Pd:27]>>[c:2]1([N:17]2[CH2:16][CH2:15][CH2:14][CH2:19][CH2:18]2)[c:3]([C:10]([F:11])([F:12])[F:13])[cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-ae06642ce9c54068a4c7c79a67e2342c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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