Acetonitrile → Tert-butyl 4-((2-(2-nitrophenyl)thiazolo[5,4-b]pyridin-6-yl)methyl)piperazine-1-carboxylate
Reaction equation
[Br:1][CH2:2][c:3]1[cH:4][c:5]2[c:6]([n:7][cH:8]1)[s:9][c:10](-[c:12]1[c:13]([N+:18](=[O:19])[O-:20])[cH:14][cH:15][cH:16][cH:17]1)[n:11]2.[C:21](=[O:22])([O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[N:28]1[CH2:29][CH2:30][NH:31][CH2:32][CH2:33]1.[CH3:34][CH2:35][N:36]([CH2:37][CH3:38])[CH2:39][CH3:40].[CH3:41][C:42]#[N:43]>>[CH2:2]([c:3]1[cH:4][c:5]2[c:6]([n:7][cH:8]1)[s:9][c:10](-[c:12]1[c:13]([N+:18](=[O:19])[O-:20])[cH:14][cH:15][cH:16][cH:17]1)[n:11]2)[N:31]1[CH2:30][CH2:29][N:28]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:33][CH2:32]1Participants
5
Sources & evidence
- ORD record
- ord-84b1b3f7984f443c984622f21e05f22e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…