Dichloromethane → (5-Methylthiophen-3-yl)(1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)methanone

HRID 1133277Notes

Reaction equation

HRID 1133277 reaction equation
[CH3:8][c:9]1[cH:10][c:11]([C:14](=[O:15])[N:16]2[CH2:17][CH2:18][O:19][C:20]3([CH2:21]2)[CH2:22][CH2:23][N:24]([C:27]([O:28][C:29]([CH3:30])([CH3:31])[CH3:32])=[O:33])[CH2:25][CH2:26]3)[cH:12][s:13]1.[Cl:34][CH2:35][Cl:36].[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[CH3:8][c:9]1[cH:10][c:11]([C:14](=[O:15])[N:16]2[CH2:17][CH2:18][O:19][C:20]3([CH2:21]2)[CH2:22][CH2:23][NH:24][CH2:25][CH2:26]3)[cH:12][s:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 57989109Tert-butyl 4-(5-methylthiophene-3-carbonyl)-1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate

Product 1

HCID 57988956(5-Methylthiophen-3-yl)(1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)methanone

Sources & evidence

ORD record
ord-9e5f42b31e8b4cabaae7e85045e0952e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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