Diethyl Ether → 2-(2,6-Dichloropyridin-4-ylmethyl)-1,1,1-trifluoro-4-(5-fluoro-2-methoxyphenyl)-4-methylpentan-2-ol
Reaction equation
[Br:2][CH2:3][c:4]1[cH:5][c:6]([Cl:11])[n:7][c:8]([Cl:10])[cH:9]1.[CH3:31][CH2:32][O:33][CH2:34][CH3:35].[F:12][C:13]([C:14]([CH2:15][C:16]([CH3:17])([CH3:18])[c:19]1[c:20]([O:26][CH3:27])[cH:21][cH:22][c:23]([F:25])[cH:24]1)=[O:28])([F:29])[F:30].[Mg:1]>>[CH2:3]([c:4]1[cH:5][c:6]([Cl:11])[n:7][c:8]([Cl:10])[cH:9]1)[C:14]([C:13]([F:12])([F:29])[F:30])([CH2:15][C:16]([CH3:17])([CH3:18])[c:19]1[c:20]([O:26][CH3:27])[cH:21][cH:22][c:23]([F:25])[cH:24]1)[OH:28]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-3af57006bd6d4a3abdd4c6ed74a49685
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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