Acetic Acid → Tert-butyl 4-oxo-3-(3-(tetrahydrofuran-2-yl)propanoyl)piperidine-1-carboxylate
Reaction equation
[CH3:1][Si:2]([N-:3][Si:4]([CH3:5])([CH3:6])[CH3:7])([CH3:8])[CH3:9].[CH3:39][C:40](=[O:41])[OH:42].[CH3:43][c:44]1[cH:45][cH:46][cH:47][cH:48][cH:49]1.[Li+:10].[O:11]=[C:12]1[CH2:13][CH2:14][N:15]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:16][CH2:17]1.[OH2:50].[n:25]1([C:30]([CH2:31][CH2:32][CH:33]2[O:34][CH2:35][CH2:36][CH2:37]2)=[O:38])[cH:26][cH:27][n:28][cH:29]1>>[O:11]=[C:12]1[CH2:13][CH2:14][N:15]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:16][CH:17]1[C:30]([CH2:31][CH2:32][CH:33]1[O:34][CH2:35][CH2:36][CH2:37]1)=[O:38]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-80102af86ab148c6b0ef574becf90550
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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