Trifluoroacetic acid → Ethyl 6-(2-aminothiazol-5-yl)-8-phenylimidazo[1,2-a]pyridine-2-carboxylate

HRID 1133639Notes

Reaction equation

HRID 1133639 reaction equation
[C:1]([O:2][C:3]([N:8]([C:4]([O:5][C:6]([CH3:7])([CH3:34])[CH3:35])=[O:36])[c:9]1[s:10][c:11](-[c:14]2[cH:15][c:16](-[c:28]3[cH:29][cH:30][cH:31][cH:32][cH:33]3)[c:17]3[n:18]([cH:19]2)[cH:20][c:21]([C:23](=[O:24])[O:25][CH2:26][CH3:27])[n:22]3)[cH:12][n:13]1)=[O:37])([CH3:38])([CH3:39])[CH3:40].[F:41][C:42]([F:43])([F:44])[C:45]([OH:46])=[O:47]>>[NH2:8][c:9]1[s:10][c:11](-[c:14]2[cH:15][c:16](-[c:28]3[cH:29][cH:30][cH:31][cH:32][cH:33]3)[c:17]3[n:18]([cH:19]2)[cH:20][c:21]([C:23](=[O:24])[O:25][CH2:26][CH3:27])[n:22]3)[cH:12][n:13]1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 58207967Ethyl 6-(2-(bis(tert-butoxycarbonyl)-amino)thiazol-5-yl)-8-phenylimidazo[1,2-a]pyridine-2-carboxylate

Product 1

HCID 58207980Ethyl 6-(2-aminothiazol-5-yl)-8-phenylimidazo[1,2-a]pyridine-2-carboxylate

Sources & evidence

ORD record
ord-0f024387e8a242448434898fd6a2bac9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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