Methane → 4-(3-Fluoropropyl)-3-(trifluoromethyl)aniline

HRID 1133645Notes

Reaction equation

[C:20].[CH3:18][OH:19].[F:1][CH2:2][CH2:3][CH2:4][c:5]1[c:6]([C:14]([F:15])([F:16])[F:17])[cH:7][c:8]([N+:11]([O-:12])=[O:13])[cH:9][cH:10]1.[Pd:21]>>[F:1][CH2:2][CH2:3][CH2:4][c:5]1[c:6]([C:14]([F:15])([F:16])[F:17])[cH:7][c:8]([NH2:11])[cH:9][cH:10]1

Participants

Reactant 4

HCID 297Methane

HCID 887Methanol

HCID 23938Palladium

HCID 593985211-(3-Fluoropropyl)-4-nitro-2-(trifluoromethyl)benzene

Product 1

HCID 593985254-(3-Fluoropropyl)-3-(trifluoromethyl)aniline

Sources & evidence

ORD record: ord-f83fb322cbed4b058645a64dda4d6696
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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