Dichloromethane → (2-{1-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-2-methyl-propyl]-2-p-tolyl-1H-imidazol-4-yl}-ethylamino)-acetic acid
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][NH:8][CH2:9][CH2:10][c:11]1[n:12][c:13](-[c:39]2[cH:40][cH:41][c:42]([CH3:45])[cH:43][cH:44]2)[n:14]([CH:16]([CH:17]([CH3:18])[CH3:19])[c:20]2[n:21][c:22]3[cH:23][c:24]([Cl:38])[cH:25][cH:26][c:27]3[c:28](=[O:37])[n:29]2[CH2:30][c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[cH:15]1)=[O:46].[CH2:54]([Cl:55])[Cl:56].[OH:47][C:48]([C:49]([F:50])([F:51])[F:52])=[O:53]>>[O:5]=[C:6]([CH2:7][NH:8][CH2:9][CH2:10][c:11]1[n:12][c:13](-[c:39]2[cH:40][cH:41][c:42]([CH3:45])[cH:43][cH:44]2)[n:14]([CH:16]([CH:17]([CH3:18])[CH3:19])[c:20]2[n:21][c:22]3[cH:23][c:24]([Cl:38])[cH:25][cH:26][c:27]3[c:28](=[O:37])[n:29]2[CH2:30][c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[cH:15]1)[OH:46]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-526a87c2f53243f598078cdef4f0e75e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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