Methyl iodide → 4-Chloro-5-methyl-1-[tri(propan-2-yl)silyl]-1H-pyrrolo[2,3-b]pyridine
Reaction equation
[CH3:26][I:27].[CH:21]([Li:22])([CH2:23][CH3:24])[CH3:25].[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][cH:7]1)[n:8]([Si:11]([CH:12]([CH3:13])[CH3:14])([CH:15]([CH3:16])[CH3:17])[CH:18]([CH3:19])[CH3:20])[cH:9][cH:10]2.[O:28]1[CH2:29][CH2:30][CH2:31][CH2:32]1>>[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][c:7]1[CH3:21])[n:8]([Si:11]([CH:12]([CH3:13])[CH3:14])([CH:15]([CH3:16])[CH3:17])[CH:18]([CH3:19])[CH3:20])[cH:9][cH:10]2Participants
5
Sources & evidence
- ORD record
- ord-e8020f9d9bec4a04ada956e2a3b41ad6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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