Dichloromethane → N-acetyl 1-(2,2-diphenyleth-1-yl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

HRID 1134614Notes

Reaction equation

HRID 1134614 reaction equation
[CH2:43]([Cl:44])[Cl:45].[CH3:29][CH2:30][N:31]([CH2:32][CH3:33])[CH2:34][CH3:35].[CH3:36][C:37](=[O:38])[O:39][C:40](=[O:41])[CH3:42].[c:1]1([CH:7]([CH2:8][CH:9]2[NH:10][CH2:11][CH2:12][c:13]3[cH:14][c:15]([O:21][CH3:22])[c:16]([O:19][CH3:20])[cH:17][c:18]32)[c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH:7]([CH2:8][CH:9]2[N:10]([C:37]([CH3:36])=[O:38])[CH2:11][CH2:12][c:13]3[cH:14][c:15]([O:21][CH3:22])[c:16]([O:19][CH3:20])[cH:17][c:18]32)[c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 7918Acetic AnhydrideHCID 8471TriethylamineHCID 223910171-(2,2-Diphenyleth-1-yl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

Product 1

HCID 9909783N-acetyl 1-(2,2-diphenyleth-1-yl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

Sources & evidence

ORD record
ord-3021282520a44f83b4ede5f66a034251
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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