Potassium Cation → 5-[[2-(2-cyano-4-fluoropyrrolidin-1-yl)-2-oxoethyl]amino]-N,N,5-trimethyl-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrole-2-carboxamide

HRID 1134740Notes

Reaction equation

HRID 1134740 reaction equation
[C:28](=[O:29])([O-:30])[O-:31].[CH3:1][N:2]([C:3](=[O:4])[N:5]1[CH2:6][CH:7]2[CH:8]([CH2:9]1)[CH2:10][C:11]([CH3:13])([NH2:14])[CH2:12]2)[CH3:15].[CH3:37][N:38]([CH3:39])[CH:40]=[O:41].[Cl:16][CH2:17][C:18](=[O:19])[N:20]1[CH:21]([C:26]#[N:27])[CH2:22][CH:23]([F:25])[CH2:24]1.[Cl:34][CH2:35][Cl:36].[K+:32].[K+:33]>>[CH3:1][N:2]([C:3](=[O:4])[N:5]1[CH2:6][CH:7]2[CH:8]([CH2:9]1)[CH2:10][C:11]([CH3:13])([NH:14][CH2:17][C:18](=[O:19])[N:20]1[CH:21]([C:26]#[N:27])[CH2:22][CH:23]([F:25])[CH2:24]1)[CH2:12]2)[CH3:15]

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 6344DichloromethaneHCID 19660Carbonate IonHCID 230753751-(2-Chloroacetyl)-4-fluoropyrrolidine-2-carbonitrileHCID 686275765-Amino-5-methyl-hexahydro-cyclopenta[c]pyrrole-2-carboxylic acid dimethylamide

Product 1

HCID 686258095-[[2-(2-cyano-4-fluoropyrrolidin-1-yl)-2-oxoethyl]amino]-N,N,5-trimethyl-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrole-2-carboxamide

Sources & evidence

ORD record
ord-b231749f77f744d1985e7d463a0fc41a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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