Sodium ion → 5-Bromo-1-(1-cyclopropyl-2-methoxyethyl)-3-[[6-(difluoromethoxy)-2,5-dimethyl-3-pyridinyl]amino]pyrazin-2-one
Reaction equation
[Br:1][c:2]1[c:3](=[O:16])[n:4]([CH:9]([CH2:10][O:11][CH3:12])[CH:13]2[CH2:14][CH2:15]2)[cH:5][c:6]([Br:8])[n:7]1.[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH3:31][Si:32]([N-:33][Si:34]([CH3:35])([CH3:36])[CH3:37])([CH3:38])[CH3:39].[F:17][CH:18]([O:19][c:20]1[c:21]([CH3:28])[cH:22][c:23]([NH2:27])[c:24]([CH3:26])[n:25]1)[F:29].[Na+:30]>>[c:2]1([NH:27][c:23]2[cH:22][c:21]([CH3:28])[c:20]([O:19][CH:18]([F:17])[F:29])[n:25][c:24]2[CH3:26])[c:3](=[O:16])[n:4]([CH:9]([CH2:10][O:11][CH3:12])[CH:13]2[CH2:14][CH2:15]2)[cH:5][c:6]([Br:8])[n:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-b1d2f71142eb45ccb78a74cdc379d320
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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