Hydrochloric Acid → N-((6-Chloro-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)-4,6-difluoropyrimidin-2-amine

HRID 1135126Notes

Reaction equation

HRID 1135126 reaction equation
[Cl:2][c:3]1[cH:4][cH:5][c:6]2[n:7]([cH:8]1)[c:9]([CH2:19][Cl:20])[c:10](-[c:12]1[cH:13][cH:14][c:15]([F:18])[cH:16][cH:17]1)[n:11]2.[ClH:1].[F:21][c:22]1[n:23][c:24]([NH2:29])[n:25][c:26]([F:28])[cH:27]1>>[Cl:2][c:3]1[cH:4][cH:5][c:6]2[n:7]([cH:8]1)[c:9]([CH2:19][NH:29][c:24]1[n:23][c:22]([F:21])[cH:27][c:26]([F:28])[n:25]1)[c:10](-[c:12]1[cH:13][cH:14][c:15]([F:18])[cH:16][cH:17]1)[n:11]2

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 12014802-Amino-4,6-difluoropyrimidineHCID 583369006-Chloro-3-(chloromethyl)-2-(4-fluorophenyl)imidazo[1,2-a]pyridine

Product 1

HCID 67028720N-((6-Chloro-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)-4,6-difluoropyrimidin-2-amine

Sources & evidence

ORD record
ord-5c3551c756e9445c9c9a1304ac762b31
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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