Potassium Cation → 3-(5-Bromo-thiazolo[5,4-b]pyridin-2-ylmethoxy)-2,6-difluoro-benzamide

HRID 1135191Notes

Reaction equation

HRID 1135191 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([n:7]1)[s:8][c:9]([CH2:11][Br:12])[n:10]2.[C:25](=[O:26])([O-:27])[O-:28].[F:13][c:14]1[c:15]([C:16](=[O:17])[NH2:18])[c:19]([F:24])[cH:20][cH:21][c:22]1[OH:23].[K+:29].[K+:30].[O:31]=[CH:32][N:33]([CH3:34])[CH3:35]>>[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([n:7]1)[s:8][c:9]([CH2:11][O:23][c:22]1[c:14]([F:13])[c:15]([C:16](=[O:17])[NH2:18])[c:19]([F:24])[cH:20][cH:21]1)[n:10]2

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 451201362,6-Difluoro-3-hydroxybenzamideHCID 866432755-Bromo-2-bromomethyl-thiazolo[5,4-b]pyridine

Product 1

HCID 866432773-(5-Bromo-thiazolo[5,4-b]pyridin-2-ylmethoxy)-2,6-difluoro-benzamide

Sources & evidence

ORD record
ord-da299b9c9f2348759c3c1ce3f3f6a0b0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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