Sodium ion → Hexahydropyrrolo[1,2-a]pyrazin-3(4h)-one

HRID 1135205Notes

Reaction equation

HRID 1135205 reaction equation
[Cl:1][CH2:2][C:3](=[O:4])[NH:5][CH2:6][CH:7]1[N:8]([C:12]([O:13][C:14]([CH3:15])([CH3:16])[CH3:17])=[O:18])[CH2:9][CH2:10][CH2:11]1.[Cl:32][CH2:33][Cl:34].[F:19][C:20]([F:21])([F:22])[C:23]([OH:24])=[O:25].[Na+:26].[Na+:27].[O-:28][C:29](=[O:30])[O-:31]>>[C:3]1(=[O:4])[NH:5][CH2:6][CH:7]2[N:8]([CH2:9][CH2:10][CH2:11]2)[CH2:12]1

Participants

6

Reactant 5

HCID 923Sodium ion2×HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 19660Carbonate IonHCID 66564632tert-Butyl 2-((2-chloroacetamido)methyl)pyrrolidine-1-carboxylate

Product 1

HCID 13607513Hexahydropyrrolo[1,2-a]pyrazin-3(4h)-one

Sources & evidence

ORD record
ord-699a8c03030e4ec6986b77065d003f55
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…