Dimethyl Sulfoxide → 5-(4-Fluorophenoxy)thiophene-2-carbonitrile

HRID 1135350Notes

Reaction equation

HRID 1135350 reaction equation
[C:19](=[O:20])([O-:21])[O-:22].[CH3:26][S:27]([CH3:28])=[O:29].[CH3:30][CH2:31][O:32][C:33](=[O:34])[CH3:35].[F:11][c:12]1[cH:13][cH:14][c:15]([OH:18])[cH:16][cH:17]1.[K+:23].[K+:24].[N+:1]([O-:2])(=[O:3])[c:4]1[cH:5][cH:6][c:7]([C:9]#[N:10])[s:8]1.[OH2:25]>>[c:4]1([O:18][c:15]2[cH:14][cH:13][c:12]([F:11])[cH:17][cH:16]2)[cH:5][cH:6][c:7]([C:9]#[N:10])[s:8]1

Participants

8

Reactant 7

HCID 679Dimethyl SulfoxideHCID 813Potassium Cation2×HCID 962WaterHCID 8857Ethyl AcetateHCID 97324-FluorophenolHCID 19660Carbonate IonHCID 5192945-Nitrothiophene-2-carbonitrile

Product 1

HCID 231305625-(4-Fluorophenoxy)thiophene-2-carbonitrile

Sources & evidence

ORD record
ord-b6601ab04e6c4bb5bd66844b1e51851f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…