Tetrahydrofuran → (2-Tert-butoxycarbonylamino-thiazol-5-yl)-propynoic acid ethyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[s:9][c:10]([C:13]#[CH:14])[cH:11][n:12]1)=[O:15].[CH2:27]1[O:28][CH2:29][CH2:30][CH2:31]1.[CH3:16][CH2:17][CH2:18][CH2:19][Li:20].[Cl:21][C:22](=[O:23])[O:24][CH2:25][CH3:26]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[s:9][c:10]([C:13]#[C:14][C:22](=[O:23])[O:24][CH2:25][CH3:26])[cH:11][n:12]1)=[O:15]Participants
5
Sources & evidence
- ORD record
- ord-7cd7ec0b84e4458abaa9c9d43b6fa683
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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