Phthalimide → 2-(2-{4-[3-(3,4-dimethoxyphenyl)-4,4-dimethyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl]piperidin-1-yl}-2-oxoethyl)-1H-isoindole-1,3(2H)-dione

HRID 1135978Notes

Reaction equation

HRID 1135978 reaction equation
[Cl:1][CH2:2][C:3](=[O:4])[N:5]1[CH2:6][CH2:7][CH:8]([N:11]2[N:12]=[C:13]([c:19]3[cH:20][c:21]([O:27][CH3:28])[c:22]([O:25][CH3:26])[cH:23][cH:24]3)[C:14]([CH3:17])([CH3:18])[C:15]2=[O:16])[CH2:9][CH2:10]1.[O:29]=[C:30]1[NH:31][C:32](=[O:33])[c:34]2[cH:35][cH:36][cH:37][cH:38][c:39]21>>[CH2:2]([C:3](=[O:4])[N:5]1[CH2:6][CH2:7][CH:8]([N:11]2[N:12]=[C:13]([c:19]3[cH:20][c:21]([O:27][CH3:28])[c:22]([O:25][CH3:26])[cH:23][cH:24]3)[C:14]([CH3:17])([CH3:18])[C:15]2=[O:16])[CH2:9][CH2:10]1)[N:31]1[C:30](=[O:29])[c:39]2[c:34]([cH:35][cH:36][cH:37][cH:38]2)[C:32]1=[O:33]

Participants

3

Reactant 2

HCID 6809PhthalimideHCID 666166092-[1-(chloroacetyl)piperidin-4-yl]-5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one

Product 1

HCID 250589092-(2-{4-[3-(3,4-dimethoxyphenyl)-4,4-dimethyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl]piperidin-1-yl}-2-oxoethyl)-1H-isoindole-1,3(2H)-dione

Sources & evidence

ORD record
ord-313034f0175442c5bc80457638de15e3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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