Toluene → 3-(4-Chloro-3-ethoxycarbonylhydrazonomethylphenyl)-2,4-dioxo-1-methyl-6-trifluoromethyl-1,2,3,4-tetrahydropyrimidine

HRID 1136036Notes

Reaction equation

HRID 1136036 reaction equation
[CH3:41][c:42]1[cH:43][cH:44][cH:45][cH:46][cH:47]1.[Cl:8][c:9]1[c:10]([CH:28]=[O:29])[cH:11][c:12](-[n:15]2[c:16](=[O:27])[n:17]([CH3:26])[c:18]([C:22]([F:23])([F:24])[F:25])[cH:19][c:20]2=[O:21])[cH:13][cH:14]1.[NH:1]([NH2:2])[C:3](=[O:4])[O:5][CH2:6][CH3:7].[c:30]1([CH3:31])[cH:32][cH:33][c:34]([S:35]([OH:36])(=[O:37])=[O:38])[cH:39][cH:40]1>>[NH:1]([N:2]=[CH:28][c:10]1[c:9]([Cl:8])[cH:14][cH:13][c:12](-[n:15]2[c:16](=[O:27])[n:17]([CH3:26])[c:18]([C:22]([F:23])([F:24])[F:25])[cH:19][c:20]2=[O:21])[cH:11]1)[C:3](=[O:4])[O:5][CH2:6][CH3:7]

Participants

5

Reactant 4

HCID 1140TolueneHCID 6101p-Toluenesulfonic acidHCID 20064Hydrazinecarboxylic acid, ethyl esterHCID 212012252-Chloro-5-[3,6-dihydro-2,6-dioxo-3-methyl-4-trifluoromethyl-1(2H)-pyrimidinyl]benzaldehyde

Product 1

HCID 702311903-(4-Chloro-3-ethoxycarbonylhydrazonomethylphenyl)-2,4-dioxo-1-methyl-6-trifluoromethyl-1,2,3,4-tetrahydropyrimidine

Sources & evidence

ORD record
ord-abeaf55e653d4b1a9dc08071a738b438
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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