Trifluoroacetic acid → (RS) 4-[3-[3-(methyl)piperidin-1-yl]propoxy]-2-[(4-chlorophenoxy)methyl]-1-[3-(piperidin-4-yl)propyl]benzimidazole
Reaction equation
[CH3:1][CH:2]1[CH2:3][N:4]([CH2:8][CH2:9][CH2:10][O:11][c:12]2[cH:13][cH:14][cH:15][c:16]3[n:17]([CH2:30][CH2:31][CH2:32][CH:33]4[CH2:34][CH2:35][N:36]([C:39]([O:40][C:41]([CH3:42])([CH3:43])[CH3:44])=[O:45])[CH2:37][CH2:38]4)[c:18]([CH2:21][O:22][c:23]4[cH:24][cH:25][c:26]([Cl:29])[cH:27][cH:28]4)[n:19][c:20]23)[CH2:5][CH2:6][CH2:7]1.[OH:46][C:47]([C:48]([F:49])([F:50])[F:51])=[O:52]>>[CH3:1][CH:2]1[CH2:3][N:4]([CH2:8][CH2:9][CH2:10][O:11][c:12]2[cH:13][cH:14][cH:15][c:16]3[n:17]([CH2:30][CH2:31][CH2:32][CH:33]4[CH2:34][CH2:35][NH:36][CH2:37][CH2:38]4)[c:18]([CH2:21][O:22][c:23]4[cH:24][cH:25][c:26]([Cl:29])[cH:27][cH:28]4)[n:19][c:20]23)[CH2:5][CH2:6][CH2:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-783e4e4a05824ddf96810a1b7f6adba2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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