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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1136168Generated: November 3, 2026

Tetrahydrofuran → Tert-butyl 3-hydroxy-3-(trifluoromethyl)pyrrolidine-1-carboxylate

https://huagongshe.com/reaction/1136168

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTetrabutylammoniumHCID 16028—
ReactantFluoride IonHCID 28179—
ReactantTert-butyl 3-oxopyrrolidine-1-carboxylateHCID 471360—
Reactant(Trifluoromethyl)trimethylsilaneHCID 552549—
ProductTert-butyl 3-hydroxy-3-(trifluoromethyl)pyrrolidine-1-carboxylateHCID 50986427—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-315059b1e7ba47e492667698b2381387
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)