Tetrahydrofuran → Tert-butyl 3-hydroxy-3-(trifluoromethyl)pyrrolidine-1-carboxylate
Reaction equation
[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH3:14][Si:15]([C:16]([F:17])([F:18])[F:19])([CH3:20])[CH3:21].[CH3:23][CH2:24][CH2:25][CH2:26][N+:27]([CH2:28][CH2:29][CH2:30][CH3:31])([CH2:32][CH2:33][CH2:34][CH3:35])[CH2:36][CH2:37][CH2:38][CH3:39].[F-:22].[O:1]=[C:2]1[CH2:3][N:4]([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:5][CH2:6]1>>[OH:1][C:2]1([C:16]([F:17])([F:18])[F:19])[CH2:3][N:4]([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:5][CH2:6]1Participants
6
Sources & evidence
- ORD record
- ord-315059b1e7ba47e492667698b2381387
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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