Dichloromethane → 4-(4-chloro-1-methylpyrazol-5-yl)-N-[1-(1,3-dioxoisoindol-2-yl)-3-[2-(trifluoromethyl)phenyl]propan-2-yl]-5-ethylthiophene-2-carboxamide
Reaction equation
[Br:59][P+:60]([N:61]1[CH2:62][CH2:63][CH2:64][CH2:65]1)([N:66]1[CH2:67][CH2:68][CH2:69][CH2:70]1)[N:71]1[CH2:72][CH2:73][CH2:74][CH2:75]1.[CH:18]([N:19]([CH2:20][CH3:21])[CH:22]([CH3:23])[CH3:24])([CH3:25])[CH3:26].[Cl:1][c:2]1[cH:3][n:4][n:5]([CH3:17])[c:6]1-[c:7]1[cH:8][c:9]([C:14](=[O:15])[OH:16])[s:10][c:11]1[CH2:12][CH3:13].[Cl:76][CH2:77][Cl:78].[NH2:27][CH:28]([CH2:29][N:30]1[C:31](=[O:40])[c:32]2[cH:33][cH:34][cH:35][cH:36][c:37]2[C:38]1=[O:39])[CH2:41][c:42]1[c:43]([C:48]([F:49])([F:50])[F:51])[cH:44][cH:45][cH:46][cH:47]1.[P-:52]([F:53])([F:54])([F:55])([F:56])([F:57])[F:58]>>[Cl:1][c:2]1[cH:3][n:4][n:5]([CH3:17])[c:6]1-[c:7]1[cH:8][c:9]([C:14](=[O:16])[NH:27][CH:28]([CH2:29][N:30]2[C:31](=[O:40])[c:32]3[cH:33][cH:34][cH:35][cH:36][c:37]3[C:38]2=[O:39])[CH2:41][c:42]2[c:43]([C:48]([F:49])([F:50])[F:51])[cH:44][cH:45][cH:46][cH:47]2)[s:10][c:11]1[CH2:12][CH3:13]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-b33af9a5595c4441ba2123900fdee63c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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