Trifluoroacetic acid → 2,2,2-Trifluoro-1-(2,8-diazaspiro[4.5]decan-8-yl)ethanone
Reaction equation
[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7].[F:8][C:9]([C:10](=[O:11])[N:12]1[CH2:13][CH2:14][C:15]2([CH2:16][CH2:17][N:18]([C:20]([O:21][C:22]([CH3:23])([CH3:24])[CH3:25])=[O:26])[CH2:19]2)[CH2:27][CH2:28]1)([F:29])[F:30]>>[F:8][C:9]([C:10](=[O:11])[N:12]1[CH2:13][CH2:14][C:15]2([CH2:16][CH2:17][NH:18][CH2:19]2)[CH2:27][CH2:28]1)([F:29])[F:30]Participants
3
Sources & evidence
- ORD record
- ord-5242976fbd4544b182ad4440ddb6b3a6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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