Ethylamine → N-Cyclopropyl-5-{3-[(1-{2-[2-(ethylamino)ethoxy]phenyl}cyclopropyl)amino]-2-oxopyrazin-1(2H)-yl}-2-fluoro-4-methylbenzamide
Reaction equation
[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[CH3:1][CH2:2][NH2:3].[Cl:4][CH2:5][CH2:6][O:7][c:8]1[c:9]([C:14]2([NH:17][c:18]3[c:19](=[O:38])[n:20](-[c:24]4[c:25]([CH3:37])[cH:26][c:27]([F:36])[c:28]([C:29](=[O:30])[NH:31][CH:32]5[CH2:33][CH2:34]5)[cH:35]4)[cH:21][cH:22][n:23]3)[CH2:15][CH2:16]2)[cH:10][cH:11][cH:12][cH:13]1.[O:39]1[CH2:40][CH2:41][O:42][CH2:43][CH2:44]1>>[CH3:1][CH2:2][NH:3][CH2:5][CH2:6][O:7][c:8]1[c:9]([C:14]2([NH:17][c:18]3[c:19](=[O:38])[n:20](-[c:24]4[c:25]([CH3:37])[cH:26][c:27]([F:36])[c:28]([C:29](=[O:30])[NH:31][CH:32]5[CH2:33][CH2:34]5)[cH:35]4)[cH:21][cH:22][n:23]3)[CH2:15][CH2:16]2)[cH:10][cH:11][cH:12][cH:13]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-5387c1a847554299a94e47ba36956dd7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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