Carbonate Ion → Ethyl 7-(tert-butoxycarbonylamino)-[1,2,4]triazolo[1,5-a]pyridine-2-carboxylate

HRID 1136578Notes

Reaction equation

HRID 1136578 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[n:5]([cH:6][cH:7]1)[n:8][c:9]([C:11](=[O:12])[O:13][CH2:14][CH3:15])[n:10]2.[C:16]([NH2:17])([O:18][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:23].[C:66](=[O:67])([O-:68])[O-:69].[Cs+:70].[Cs+:71].[O:116]=[C:117]([CH:118]=[CH:119][c:120]1[cH:121][cH:122][cH:123][cH:124][cH:125]1)[CH:126]=[CH:127][c:128]1[cH:129][cH:130][cH:131][cH:132][cH:133]1.[O:72]1[CH2:73][CH2:74][O:75][CH2:76][CH2:77]1.[O:80]=[C:81]([CH:82]=[CH:83][c:84]1[cH:85][cH:86][cH:87][cH:88][cH:89]1)[CH:90]=[CH:91][c:92]1[cH:93][cH:94][cH:95][cH:96][cH:97]1.[O:98]=[C:99]([CH:100]=[CH:101][c:102]1[cH:103][cH:104][cH:105][cH:106][cH:107]1)[CH:108]=[CH:109][c:110]1[cH:111][cH:112][cH:113][cH:114][cH:115]1.[Pd:78].[Pd:79].[c:24]1([P:25]([c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)[c:32]2[c:33]3[c:57]([cH:58][cH:59][cH:60]2)[C:54]([CH3:55])([CH3:56])[c:36]2[c:35]([c:40]([P:41]([c:42]4[cH:43][cH:44][cH:45][cH:46][cH:47]4)[c:48]4[cH:49][cH:50][cH:51][cH:52][cH:53]4)[cH:39][cH:38][cH:37]2)[O:34]3)[cH:61][cH:62][cH:63][cH:64][cH:65]1>>[c:2]1([NH:17][C:16]([O:18][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:23])[cH:3][c:4]2[n:5]([cH:6][cH:7]1)[n:8][c:9]([C:11](=[O:12])[O:13][CH2:14][CH3:15])[n:10]2

Participants

9

Reactant 8

HCID 19660Carbonate IonHCID 23938Palladium2×HCID 312751,4-DioxaneHCID 77922tert-Butyl carbamateHCID 95417Dibenzylidene acetone3×HCID 104967Cesium cation2×HCID 6360441,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine)HCID 67774638Ethyl 7-bromo-(1,2,4)triazolo(1,5-a)pyridine-2-carboxylate

Product 1

HCID 67776374Ethyl 7-(tert-butoxycarbonylamino)-[1,2,4]triazolo[1,5-a]pyridine-2-carboxylate

Sources & evidence

ORD record
ord-2bba789b80da4088a7ad6739b766e4f4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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