Dichloromethane → 5-chloro-2-(4-methoxy-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl)benzonitrile
Reaction equation
[CH3:1][O:2][c:3]1[c:4]2[c:5]([n:6][cH:7][n:8]1)[CH2:9][CH2:10][NH:11][CH2:12]2.[Cl:13][c:14]1[cH:15][cH:16][c:17]([F:22])[c:18]([C:19]#[N:20])[cH:21]1.[Cl:34][CH2:35][Cl:36].[N:23]12[CH2:24][CH2:25][CH2:26][N:27]=[C:28]1[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]2>>[CH3:1][O:2][c:3]1[c:4]2[c:5]([n:6][cH:7][n:8]1)[CH2:9][CH2:10][N:11]([c:17]1[cH:16][cH:15][c:14]([Cl:13])[cH:21][c:18]1[C:19]#[N:20])[CH2:12]2Participants
5
Sources & evidence
- ORD record
- ord-ce842d13fd42459597e16af2698b8f19
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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