Methanol → 4H-Pyrimido(6,1-a)isoquinolin-4-one, 6,7-dihydro-9,10-dimethoxy-2-((1-methylethyl)(2,4,6-trimethylphenyl)amino)-

HRID 1136819Notes

Reaction equation

HRID 1136819 reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:10]([cH:11][c:12]1[O:13][CH3:14])-[c:9]1[n:8]([c:18](=[O:19])[n:17][c:16]([NH:20][c:21]3[c:22]([CH3:29])[cH:23][c:24]([CH3:28])[cH:25][c:26]3[CH3:27])[cH:15]1)[CH2:7][CH2:6]2.[CH3:30][N:31]([CH3:32])[CH:33]=[O:34].[CH3:41][OH:42].[CH:37]([CH3:38])([CH3:39])[I:40].[H-:35].[Na+:36]>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:10]([cH:11][c:12]1[O:13][CH3:14])-[c:9]1[n:8]([c:18](=[O:19])[n:17][c:16]([N:20]([c:21]3[c:22]([CH3:29])[cH:23][c:24]([CH3:28])[cH:25][c:26]3[CH3:27])[CH:37]([CH3:38])[CH3:39])[cH:15]1)[CH2:7][CH2:6]2

Participants

7

Reactant 6

HCID 887MethanolHCID 923Sodium ionHCID 6228DimethylformamideHCID 6362Isopropyl iodideHCID 166653HydrideHCID 18694579,10-dimethoxy-2-(2,4,6-trimethylanilino)-6,7-dihydropyrimido[6,1-a]isoquinolin-4-one

Product 1

HCID 30681544H-Pyrimido(6,1-a)isoquinolin-4-one, 6,7-dihydro-9,10-dimethoxy-2-((1-methylethyl)(2,4,6-trimethylphenyl)amino)-

Sources & evidence

ORD record
ord-a322d0ee015849e0bc03cc4e35f7455c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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