Dichloromethane → 3-(2-Fluoro-3-((4-(2-isopropylthiazole-4-carbonyl)-1-oxa-4,9-diazaspiro[5.5]undecan-9-yl)methyl)phenethoxy)propanoic acid
Reaction equation
[Cl:49][CH2:50][Cl:51].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7].[F:8][c:9]1[c:10]([CH2:11][CH2:12][O:13][CH2:14][CH2:15][C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[cH:23][cH:24][cH:25][c:26]1[CH2:27][N:28]1[CH2:29][CH2:30][C:31]2([CH2:32][N:33]([C:37](=[O:38])[c:39]3[n:40][c:41]([CH:44]([CH3:45])[CH3:46])[s:42][cH:43]3)[CH2:34][CH2:35][O:36]2)[CH2:47][CH2:48]1>>[F:8][c:9]1[c:10]([CH2:11][CH2:12][O:13][CH2:14][CH2:15][C:16](=[O:17])[OH:18])[cH:23][cH:24][cH:25][c:26]1[CH2:27][N:28]1[CH2:29][CH2:30][C:31]2([CH2:32][N:33]([C:37](=[O:38])[c:39]3[n:40][c:41]([CH:44]([CH3:45])[CH3:46])[s:42][cH:43]3)[CH2:34][CH2:35][O:36]2)[CH2:47][CH2:48]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-d0561465a78a4ce1887e1601bc7fe09f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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