Dichloromethane → 4-(Tert-butyldimethylsilyloxymethyl)pyridine

HRID 1137263Notes

Reaction equation

HRID 1137263 reaction equation
[C:16]([CH3:17])([CH3:18])([CH3:19])[Si:20]([CH3:21])([CH3:22])[Cl:23].[CH3:9][CH2:10][N:11]([CH2:12][CH3:13])[CH2:14][CH3:15].[Cl:24][CH2:25][Cl:26].[n:1]1[cH:2][cH:3][c:4]([CH2:7][OH:8])[cH:5][cH:6]1>>[n:1]1[cH:2][cH:3][c:4]([CH2:7][O:8][Si:20]([C:16]([CH3:17])([CH3:18])[CH3:19])([CH3:21])[CH3:22])[cH:5][cH:6]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 114724-HydroxymethylpyridineHCID 28928tert-Butyldimethylsilyl chloride

Product 1

HCID 109878804-(Tert-butyldimethylsilyloxymethyl)pyridine

Sources & evidence

ORD record
ord-606168bd9c174945a7942ccf082ea373
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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