Tetrahydrofuran → Tert-butyl 2-fluoro-4-(3,3,3-trifluoroprop-1-enyl)benzoate

HRID 1137590Notes

Reaction equation

HRID 1137590 reaction equation
[CH2:2]([N+:3]([CH2:4][CH2:5][CH2:6][CH3:7])([CH2:8][CH2:9][CH2:10][CH3:11])[CH2:12][CH2:13][CH2:14][CH3:15])[CH2:16][CH2:17][CH3:18].[CH2:54]1[O:55][CH2:56][CH2:57][CH2:58]1.[F-:1].[F:19][c:20]1[c:21]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[cH:29][cH:30][c:31]([CH:33]=[O:34])[cH:32]1.[F:35][C:36]([CH2:37][P:38](=[O:39])([c:40]1[cH:41][cH:42][cH:43][cH:44][cH:45]1)[c:46]1[cH:47][cH:48][cH:49][cH:50][cH:51]1)([F:52])[F:53]>>[F:19][c:20]1[c:21]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[cH:29][cH:30][c:31]([CH:33]=[CH:37][C:36]([F:35])([F:52])[F:53])[cH:32]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 11323568Diphenyl(2,2,2-trifluoroethyl)phosphine oxideHCID 86607392tert-Butyl 2-fluoro-4-formylbenzoate

Product 1

HCID 68704413Tert-butyl 2-fluoro-4-(3,3,3-trifluoroprop-1-enyl)benzoate

Sources & evidence

ORD record
ord-7d1dd02ddc054f05becb2fcb9af9fbf1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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