Benzene → Tert-butyl 4-benzyl-3-oxopiperazine-1-carboxylate

HRID 1137708Notes

Reaction equation

HRID 1137708 reaction equation
[C:16]([CH3:17])([CH3:18])([CH3:19])[O:20][C:21](=[O:22])[O:23][N:24]=[C:25]([c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1)[C:32]([NH2:33])=[O:34].[ClH:1].[c:2]1([CH2:8][N:9]2[C:10](=[O:15])[CH2:11][NH:12][CH2:13][CH2:14]2)[cH:3][cH:4][cH:5][cH:6][cH:7]1.[cH:35]1[cH:36][cH:37][cH:38][cH:39][cH:40]1>>[c:2]1([CH2:8][N:9]2[C:10](=[O:15])[CH2:11][N:12]([C:21]([O:20][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:22])[CH2:13][CH2:14]2)[cH:3][cH:4][cH:5][cH:6][cH:7]1

Participants

5

Reactant 4

HCID 241BenzeneHCID 313Hydrochloric AcidHCID 15143031-Benzylpiperazin-2-oneHCID 537190902-(t-Butoxycarbonyloxyimino)-2-phenylacetamide

Product 1

HCID 10891590Tert-butyl 4-benzyl-3-oxopiperazine-1-carboxylate

Sources & evidence

ORD record
ord-d3640572dd504a3697b274fe963c4b7d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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