Sodium ion → 3-Bromo-5-(4-methoxyphenyl)pyridine

HRID 1137741Notes

Reaction equation

HRID 1137741 reaction equation
[Br:1][c:2]1[cH:3][n:4][cH:5][c:6]([Br:7])[cH:8]1.[C:20](=[O:21])([O-:22])[O-:23].[CH3:26][C:27]#[N:28].[CH3:9][O:10][c:11]1[cH:12][cH:13][c:14]([B:17]([OH:18])[OH:19])[cH:15][cH:16]1.[Na+:24].[Na+:25].[cH:29]1[cH:30][cH:31][c:32]([P:33]([Pd:34]([P:35]([c:36]2[cH:37][cH:38][cH:39][cH:40][cH:41]2)([c:42]2[cH:43][cH:44][cH:45][cH:46][cH:47]2)[c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)([P:54]([c:55]2[cH:56][cH:57][cH:58][cH:59][cH:60]2)([c:61]2[cH:62][cH:63][cH:64][cH:65][cH:66]2)[c:67]2[cH:68][cH:69][cH:70][cH:71][cH:72]2)[P:73]([c:74]2[cH:75][cH:76][cH:77][cH:78][cH:79]2)([c:80]2[cH:81][cH:82][cH:83][cH:84][cH:85]2)[c:86]2[cH:87][cH:88][cH:89][cH:90][cH:91]2)([c:92]2[cH:93][cH:94][cH:95][cH:96][cH:97]2)[c:98]2[cH:99][cH:100][cH:101][cH:102][cH:103]2)[cH:104][cH:105]1>>[c:2]1(-[c:14]2[cH:13][cH:12][c:11]([O:10][CH3:9])[cH:16][cH:15]2)[cH:3][n:4][cH:5][c:6]([Br:7])[cH:8]1

Participants

7

Reactant 6

HCID 923Sodium ion2×HCID 6342AcetonitrileHCID 19660Carbonate IonHCID 693693,5-DibromopyridineHCID 201262(4-Methoxyphenyl)boronic acidHCID 178420554HCID 178420554, compound

Product 1

HCID 120670673-Bromo-5-(4-methoxyphenyl)pyridine

Sources & evidence

ORD record
ord-a597b160851f4c58b9e743cbd6483ebc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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