Dichloromethane → tert-butyl (3RS,4RS)-4-[4-(2,2-dimethyl-propionyloxymethyl)-phenyl]-3-(naphthalen-2-ylmethoxy)-piperidine-1-carboxylate
Reaction equation
[C:41]([C:42]([CH3:43])([CH3:44])[CH3:45])(=[O:46])[Cl:47].[CH2:48]([Cl:49])[Cl:50].[CH3:34][CH2:35][N:36]([CH2:37][CH3:38])[CH2:39][CH3:40].[OH:1][CH2:2][c:3]1[cH:4][cH:5][c:6]([CH:9]2[CH:10]([O:22][CH2:23][c:24]3[cH:25][c:26]4[cH:27][cH:28][cH:29][cH:30][c:31]4[cH:32][cH:33]3)[CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]2)[cH:7][cH:8]1>>[O:1]([CH2:2][c:3]1[cH:4][cH:5][c:6]([CH:9]2[CH:10]([O:22][CH2:23][c:24]3[cH:25][c:26]4[cH:27][cH:28][cH:29][cH:30][c:31]4[cH:32][cH:33]3)[CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]2)[cH:7][cH:8]1)[C:41]([C:42]([CH3:43])([CH3:44])[CH3:45])=[O:46]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-1314d1ec5f714e9a8d4506da6c6f1b6d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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