Sodium ion → Tert-butyl 4-(3-bromophenoxy)-2-methylpiperidine-1-carboxylate

HRID 1137998Notes

Reaction equation

HRID 1137998 reaction equation
[Br:18][c:19]1[cH:20][c:21]([F:25])[cH:22][cH:23][cH:24]1.[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH3:15])[CH2:10][CH:11]([OH:14])[CH2:12][CH2:13]1.[CH3:26][N:27]1[CH2:28][CH2:29][CH2:30][C:31]1=[O:32].[H-:16].[Na+:17]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH3:15])[CH2:10][CH:11]([O:14][c:21]2[cH:20][c:19]([Br:18])[cH:24][cH:23][cH:22]2)[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 13387N-methyl-2-pyrrolidoneHCID 140821-Bromo-3-fluorobenzeneHCID 166653HydrideHCID 22181172Tert-butyl 4-hydroxy-2-methylpiperidine-1-carboxylate

Product 1

HCID 69063263Tert-butyl 4-(3-bromophenoxy)-2-methylpiperidine-1-carboxylate

Sources & evidence

ORD record
ord-d92abbe4eedb40a8be52324385d3e7a3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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