Methanol → 1'-(diphenylmethyl)-6-hydroxyspiro[1-benzofuran-3,3'-indol]-2'(1'H)-one

HRID 1138214Notes

Reaction equation

HRID 1138214 reaction equation
[C:40]([O:41][CH2:42][CH3:43])(=[O:44])[CH3:45].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]2[c:12]([cH:38][cH:39]1)[C:13]1([CH2:14][O:15]2)[C:16](=[O:37])[N:17]([CH:24]([c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[c:18]2[cH:19][cH:20][cH:21][cH:22][c:23]21.[CH3:46][OH:47]>>[OH:8][c:9]1[cH:10][c:11]2[c:12]([cH:38][cH:39]1)[C:13]1([CH2:14][O:15]2)[C:16](=[O:37])[N:17]([CH:24]([c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[c:18]2[cH:19][cH:20][cH:21][cH:22][c:23]21

Participants

4

Reactant 3

HCID 887MethanolHCID 8857Ethyl AcetateHCID 461941811'-benzhydryl-6-(benzyloxy)-2H-spiro[benzofuran-3,3'-indolin]-2'-one

Product 1

HCID 593526351'-(diphenylmethyl)-6-hydroxyspiro[1-benzofuran-3,3'-indol]-2'(1'H)-one

Sources & evidence

ORD record
ord-6c10ea27dcaa466cb38ac25b5db518b1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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