Pyridine → (RS) 1-Chlorocarbonyl-2-ethyl-4-tert-butoxycarbonylpiperazine

HRID 1138289Notes

Reaction equation

HRID 1138289 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH2:14][CH3:15])[NH:11][CH2:12][CH2:13]1.[Cl:22][C:23]([Cl:24])([O:25][C:26](=[O:27])[O:28][C:29]([Cl:30])([Cl:31])[Cl:32])[Cl:33].[Cl:34][CH2:35][Cl:36].[cH:16]1[cH:17][cH:18][n:19][cH:20][cH:21]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH2:14][CH3:15])[N:11]([C:23]([Cl:22])=[O:25])[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 1049PyridineHCID 6344DichloromethaneHCID 94429TriphosgeneHCID 22219867tert-Butyl 3-ethylpiperazine-1-carboxylate

Product 1

HCID 22219864(RS) 1-Chlorocarbonyl-2-ethyl-4-tert-butoxycarbonylpiperazine

Sources & evidence

ORD record
ord-8a6f6ae378994c58b6510f5dd80ba3e5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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