Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1138553Generated: November 4, 2026

Dichloromethane → tert-butyl (3SR,4RS,5RS)-4-[4-(2-benzyloxy-ethoxymethyl)-phenyl]-3-hydroxymethyl-5-(naphthalen-2-ylmethoxy)-piperidine-1-carboxylate

https://huagongshe.com/reaction/1138553

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTrifluoroacetic acidHCID 6422—
ReactantTrifluoroacetic anhydrideHCID 9845—
Reactant1-Benzyloxy-2-iodoethaneHCID 10355314—
Reactanttert-butyl (3RS,4RS,5SR)-4-[4-(2-benzyloxy-ethoxymethyl)-phenyl]-3-(naphthalen-2-ylmethoxy)-5-trityloxymethyl-piperidine-1-carboxylateHCID 86604536—
Producttert-butyl (3SR,4RS,5RS)-4-[4-(2-benzyloxy-ethoxymethyl)-phenyl]-3-hydroxymethyl-5-(naphthalen-2-ylmethoxy)-piperidine-1-carboxylateHCID 86604535—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-8b95f32a594d42cfb05dd40f9123de81
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)