Ammonia → 1-(Phenylmethyl)-4-[3-(trifluoromethyl)phenyl]-4-piperidinemethanamine
Reaction equation
[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[N:9]1[CH2:10][CH2:11][C:12]([C:15]#[N:16])([c:17]2[cH:18][c:19]([C:23]([F:24])([F:25])[F:26])[cH:20][cH:21][cH:22]2)[CH2:13][CH2:14]1.[CH3:28][OH:29].[ClH:1].[NH3:27].[Ni:30]>>[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[N:9]1[CH2:10][CH2:11][C:12]([CH2:15][NH2:16])([c:17]2[cH:18][c:19]([C:23]([F:24])([F:25])[F:26])[cH:20][cH:21][cH:22]2)[CH2:13][CH2:14]1Participants
6
Sources & evidence
- ORD record
- ord-425fa1d493854f999e2d0341c02fb502
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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