Chloroform → 1-(2-Chloro-6-morpholinopyrimidin-4-yl)piperidin-2-one

HRID 113874Notes

Reaction equation

HRID 113874 reaction equation
[CH:25]([N:26]([CH2:27][CH3:28])[CH:29]([CH3:30])[CH3:31])([CH3:32])[CH3:33].[CH:55]([Cl:56])([Cl:57])[Cl:58].[Cl:34][c:35]1[n:36][c:37]([N:49]2[CH2:50][CH2:51][O:52][CH2:53][CH2:54]2)[cH:38][c:39]([NH:41][CH2:42][CH2:43][CH2:44][CH2:45][C:46](=[O:47])[OH:48])[n:40]1.[P-:1]([F:2])([F:3])([F:4])([F:5])([F:6])[F:7].[n:8]1([O:9][C:10]([N:11]([CH3:12])[CH3:13])=[N+:14]([CH3:15])[CH3:16])[c:17]2[n:18][cH:19][cH:20][cH:21][c:22]2[n:23][n:24]1>>[Cl:34][c:35]1[n:36][c:37]([N:49]2[CH2:50][CH2:51][O:52][CH2:53][CH2:54]2)[cH:38][c:39]([N:41]2[CH2:42][CH2:43][CH2:44][CH2:45][C:46]2=[O:47])[n:40]1

Participants

6

Reactant 5

HCID 6212ChloroformHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 866458885-(2-Chloro-6-morpholinopyrimidin-4-ylamino)pentanoic acid

Product 1

HCID 866458891-(2-Chloro-6-morpholinopyrimidin-4-yl)piperidin-2-one

Sources & evidence

ORD record
ord-4a9e87063cf24c1392efeff0bad3a316
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…