Formic Acid → 2-(5-Chloro-2-fluoro-phenyl)-4-[6'-(4-methyl-piperazin-1-yl)-[3,3']bipyridinyl-5-yl]-[1,8]naphthyridine
Reaction equation
[CH2:38]=[O:39].[CH:42]([OH:43])=[O:44].[Cl:2][c:3]1[cH:4][cH:5][c:6]([F:37])[c:7](-[c:9]2[n:10][c:11]3[n:12][cH:13][cH:14][cH:15][c:16]3[c:17](-[c:19]3[cH:20][c:21](-[c:25]4[cH:26][n:27][c:28]([N:31]5[CH2:32][CH2:33][NH:34][CH2:35][CH2:36]5)[cH:29][cH:30]4)[cH:22][n:23][cH:24]3)[cH:18]2)[cH:8]1.[ClH:1].[Na+:41].[OH-:40]>>[Cl:2][c:3]1[cH:4][cH:5][c:6]([F:37])[c:7](-[c:9]2[n:10][c:11]3[n:12][cH:13][cH:14][cH:15][c:16]3[c:17](-[c:19]3[cH:20][c:21](-[c:25]4[cH:26][n:27][c:28]([N:31]5[CH2:32][CH2:33][N:34]([CH3:38])[CH2:35][CH2:36]5)[cH:29][cH:30]4)[cH:22][n:23][cH:24]3)[cH:18]2)[cH:8]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-60715b65aab94ffd9462463c00bf18da
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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