Acetate → N-[5-(2-tert-butyl-pyridin-4-yl)-4-methyl-thiazol-2-yl]acetamide

HRID 1138991Notes

Reaction equation

HRID 1138991 reaction equation
[Br:17][c:18]1[cH:19][c:20]([C:24]([CH3:25])([CH3:26])[CH3:27])[n:21][cH:22][cH:23]1.[C:11](=[O:12])([O-:13])[O-:14].[C:1]([CH3:2])(=[O:3])[NH:4][c:5]1[s:6][cH:7][c:8]([CH3:10])[n:9]1.[Cs+:15].[Cs+:16].[O-:34][C:35]([CH3:36])=[O:37].[O-:38][C:39]([CH3:40])=[O:41].[O:28]=[CH:29][N:30]([CH3:31])[CH3:32].[Pd+2:33]>>[C:1]([CH3:2])(=[O:3])[NH:4][c:5]1[s:6][c:7](-[c:18]2[cH:19][c:20]([C:24]([CH3:25])([CH3:26])[CH3:27])[n:21][cH:22][cH:23]2)[c:8]([CH3:10])[n:9]1

Participants

8

Reactant 7

HCID 175Acetate2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 280907N-(4-Methylthiazol-2-yl)acetamideHCID 457878674-Bromo-2-tert-butylpyridine

Product 1

HCID 59293656N-[5-(2-tert-butyl-pyridin-4-yl)-4-methyl-thiazol-2-yl]acetamide

Sources & evidence

ORD record
ord-2e82bb22ff2748179577163b8ecfe983
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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