Tetrahydrofuran → 2-(1,1-dimethylethoxycarbonylamino)-N-[2-(4-hydroxy-3-methoxy-phenyl)-ethyl]-3-methylbutyramide

HRID 1139325Notes

Reaction equation

HRID 1139325 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([O:32][CH3:33])[cH:11][c:12]([CH2:15][CH2:16][NH:17][C:18]([CH:19]([CH:20]([CH3:21])[CH3:22])[NH:23][C:24](=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30])=[O:31])[cH:13][cH:14]1.[H:39][H:40].[O:34]1[CH2:35][CH2:36][CH2:37][CH2:38]1>>[OH:8][c:9]1[c:10]([O:32][CH3:33])[cH:11][c:12]([CH2:15][CH2:16][NH:17][C:18]([CH:19]([CH:20]([CH3:21])[CH3:22])[NH:23][C:24](=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30])=[O:31])[cH:13][cH:14]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 178418361HCID 178418361, compoundHCID 178491213tert-butyl N-[1-[2-(3-methoxy-4-phenylmethoxyphenyl)ethylamino]-3-methyl-1-oxobutan-2-yl]carbamate

Product 1

HCID 184120642-(1,1-dimethylethoxycarbonylamino)-N-[2-(4-hydroxy-3-methoxy-phenyl)-ethyl]-3-methylbutyramide

Sources & evidence

ORD record
ord-775fbae17c7c45db840fb44c51a53663
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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