Hydrochloric Acid → Urea, N-[[(1R)-6-[(3-fluorophenyl)sulfonyl]-1,2,3,4-tetrahydro-1-naphthalenyl]methyl]-;Urea, N-[[(1R)-6-[(3-fluorophenyl)sulfonyl]-1,2,3,4-tetrahydro-1-naphthalenyl]methyl]-

HRID 1139559Notes

Reaction equation

HRID 1139559 reaction equation
[ClH:1].[F:2][c:3]1[cH:4][c:5]([S:9](=[O:10])(=[O:11])[c:12]2[cH:13][c:14]3[c:19]([cH:20][cH:21]2)[CH:18]([CH2:22][NH2:23])[CH2:17][CH2:16][CH2:15]3)[cH:6][cH:7][cH:8]1.[K:24][O:25][C:26]#[N:27].[OH2:28]>>[F:2][c:3]1[cH:4][c:5]([S:9](=[O:10])(=[O:11])[c:12]2[cH:13][c:14]3[c:19]([cH:20][cH:21]2)[CH:18]([CH2:22][NH:23][C:26](=[O:25])[NH2:27])[CH2:17][CH2:16][CH2:15]3)[cH:6][cH:7][cH:8]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 962WaterHCID 59021794C-[6-(3-Fluoro-benzenesulfonyl)-1,2,3,4-tetrahydro-naphthalen-1-yl]methylamineHCID 178418250HCID 178418250, compound

Product 1

HCID 24850467Urea, N-[[(1R)-6-[(3-fluorophenyl)sulfonyl]-1,2,3,4-tetrahydro-1-naphthalenyl]methyl]-;Urea, N-[[(1R)-6-[(3-fluorophenyl)sulfonyl]-1,2,3,4-tetrahydro-1-naphthalenyl]methyl]-

Sources & evidence

ORD record
ord-981addc137214f489f947eadbacb48eb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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