Methanol → 5-Amino-2-(2-methoxy-ethoxy)-6-methylamino-N-(trans-4-trifluoromethyl-cyclohexyl)-nicotinamide
Reaction equation
[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH3:1][O:2][CH2:3][CH2:4][O:5][c:6]1[c:7]([C:8](=[O:9])[NH:10][CH:11]2[CH2:12][CH2:13][CH:14]([C:17]([F:18])([F:19])[F:20])[CH2:15][CH2:16]2)[cH:21][c:22]([N+:27]([O-:28])=[O:29])[c:23]([NH:25][CH3:26])[n:24]1.[CH3:30][OH:31]>>[CH3:1][O:2][CH2:3][CH2:4][O:5][c:6]1[c:7]([C:8](=[O:9])[NH:10][CH:11]2[CH2:12][CH2:13][CH:14]([C:17]([F:18])([F:19])[F:20])[CH2:15][CH2:16]2)[cH:21][c:22]([NH2:27])[c:23]([NH:25][CH3:26])[n:24]1Participants
4
Sources & evidence
- ORD record
- ord-2f957b1576a043acbe33bb703563acb4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
Loading…